新生儿缺氧缺血性脑病早期干预的效果

The observation on the effects of early intervention on infants with hypoxic-ischemic encephalopathy

目的探讨通过早期干预对新生儿缺氧缺血性脑病(HIE)发育状况的疗效。方法将96例观察对象随机分到两组,早期干预组在新生儿期即开始接受系统的干预;晚期干预在4个月以后开始治疗,1岁时测量他们的的行为发育商(DQ)和发育年龄(DA),并进行比较。结果晚期干预组发育异常率为27.7%,高于早期干预组的10.45%(χ2=4.597,P=0.032),干预疗效与开始接受治疗的年龄(H=23.92,P<0.001)、治疗疗程(H=0.990,P<0.001)有关。结论对新生儿缺氧缺血性脑病患者早期干预治疗能有效改善智力及运动发育。

Objective To explore the treatment efficiency of early intervention to the infants with hypoxieisehemic eneephalopathy （HIE）.Method Ninety-six observation subjects were divided into two groups randomly,l.e the people from early intervention group received system intervention immediately after their birth; the people from later intervention group received intervention late four months after their birth. The development quotient and development age were measured when the observation subjects were one year old.Results The developmel^t abnorlaat rate was significantly higher in early interrelation group （x^2=4.597,P=0.032）. The intervention therapy was related with the age when they begin to receive the treatment （H=23.92,P〈0.001） and the therapy period （H=0.990,P〈0.001）.Conclusion The intelligenee and activity development of infants with HIE call be improved after early intervention.