摘要
炎性肠病是一种病因不明的肠道非特异性炎性疾病,主要包括克罗恩病和溃疡性结肠炎。近年来研究发现,血管生成在炎性肠病中具有十分重要的意义。许多因子可以促进血管的生成,诸如纤维生长因子-2、白细胞介素-8、血小板源性生长因子、转化生长因子β,特别是血管内皮生长因子。作者就炎性肠病血管生成的相关因子作一综述。
Inflammatory bowel disease (IBD), the precise etiology of which remains unknown, is comprised of two forms of chronic intestinal inflammation, ulcerative colitis and Crohn's disease. Recent researches suggest that angiopoiesis plays an important role in the development of IBD. Many cytokines can enhance angiopoiesis, such as fibroblast growth factor-2, interleukin-8, transforming factor-β and particularly vascular endothelial platelet-derived growth factor, factor. This review summarizes the angiopoietic factors correlated with IBD. K
出处
《医学研究生学报》
CAS
2007年第11期1223-1226,共4页
Journal of Medical Postgraduates
基金
南京军区南京总医院科研基金资助项目(批准号:2005111)
关键词
血管形成因子
炎性肠病
血管内皮生长因子
Angiopoietic factor
Inflammatory bowel disease
Vascular endothelial growth factor