蜂胶牙膏对龈上菌斑抑制效果的临床试验

Clinical study on effect of toothpaste with propolis in controlling plaque

目的评价蜂胶牙膏在抑制龈上菌斑形成的临床效果。方法40名志愿者随机分为两组,即蜂胶牙膏组和空白牙膏组,双盲法评价1周与4周后的刷牙效果。结果使用蜂胶牙膏4周后,试验组全口平均菌斑指数持续下降,第4周与第1周比较差异具有统计学意义(P=0.0325)。1周后,两组菌斑指数的降低率无统计学差异;4周后,蜂胶牙膏组平均菌斑指数的降低率与空白牙膏组比较差异有统计学意义(P=0.0459)。结论蜂胶牙膏能有效抑制龈上菌斑形成,优于不含蜂胶的空白牙膏。

Objective To estimate the clinical effect of the toothpaste with propolis in controlling plaque. Methods A double blind, controlled clinical trial was performed with a total of forty volunteers. The subjects were divided into two groups randomly, propolis group and blank group. One week and four weeks later, the effects of both groups were estimated. Results Four weeks later, plaque index（PLI） of the propolis group continually decreased. There was significant difference between one weeks＂ PLI and four weeks＂ （P^0. 032 5）. One week later, there was no statistically significant difference in decrease rate of plaque between the two groups. Four weeks later, there was statistically significant difference between the two groups（P=0. 045 9）. Conclusion The toothpaste with propolis has significant effect in controlling plaque. The effect of propolis group is better than the blank group＇s.