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住院患者血浆头孢菌素IgG和IgM抗体检测分析

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摘要 目的调查住院患者头孢菌素IgG和IgM抗体免疫现况。方法采用微柱凝胶抗人球蛋白法对240例住院患者分别进行血浆头孢唑啉、头孢呋辛、头孢哌酮IgG和IgM抗体检测。结果患者血浆头孢唑啉、头孢呋辛、头孢哌酮阳性率分别为0%(0/240)、4.58%(11/240)、6.25%(15/240),统计结果显示患者血浆头孢呋辛、头孢哌酮抗体阳性率高于头孢唑啉(P均<0.01);未发现头孢唑啉、头孢呋辛和头孢哌酮抗体之间存在共阳性现象(共阳性率均为0%)。结论患者头孢呋辛、头孢哌酮的IgG和IgM抗体免疫相对比较严重,而头孢唑啉IgG和IgM抗体免疫相对乐观;上述3种头孢菌素IgG和IgM抗体间很可能不存在交叉反应。
出处 《重庆医学》 CAS CSCD 2007年第13期1318-1319,共2页 Chongqing medicine
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