摘要
应用聚合酶反应技术检测19例抗－HBC阳性，HBsAg阳性之母婴HBVDNA。结果显示，2／6HBc阳性母亲1／6抗－HBc阴性婴儿，1例抗HBc，抗－HBc，HBeAg阳性母亲的HB－VDNA阳性。证实了抗－HBc阳性，HBsAg阴性母亲不仅体内存在HBVDNA，而且经过子宫内胎盘传播导致了婴儿的宫内感染，说明不仅HBsAg阳性母亲，而且HBsAg阴性但抗－HBc阳性母亲同样可引起乙肝的宫内感染，对乙肝母婴传播的深入研究提供了资料。对今后研究乙肝病毒母婴垂直传播。
Hepatitis B virus (HBV) DNA in sera was detected by means of polymerase chain reaction (PCR) in 19 pairs of anti-HBc positive, HBeAg negative mothers and their infants. The results indicated that serum HBVDNA was found in 2/6 of anti-HBc positive mothers, 1/6 of anti-Hbc positive infants and one of anti-HBc, anti-Hbs, HBeAg positive mother respectively. That denoted the possibility of not only the presence of HBVDNA among anti-HBc positive, HBsAg negative mothers but also the existence of HBV transplacental transmission in utero.
出处
《新生儿科杂志》
1997年第3期100-102,共3页
The Journal of Neonatology
