无痛人流术后酗酒患者对异丙酚耐药性的临床观察

Clinical observation of the patients with hard - drinking history has resistance to use propofol in the painless induced abortion

目的 观察有酗酒史患者在无痛人流术中使用异丙酚的临床效果。方法 随机选择门诊初孕、既往体健、具有不同程度慢性酗酒史患者30例作为研究组（A组）,另外选30例无饮酒史初孕、既往体健患者作为对照组（B组）,观察两组病人在无痛人流术中异丙酚的应用效果及不良反应。结果 A组患者异丙酚平均总用量多于B组,镇痛效果较B组差,不良反应发生率较B组高。结论 在无痛人流术中有酗酒史患者对异丙酚具有一定的耐药性。

Objective To explore the effect that use propofol in painless induced abortion for patients with hard -drinking history. Methods Randomly chose 30 outpatients who are first pregnant and healthy in the past,hut hard different degress of hard -drinking as the research group（A group）. In addition,30 other outpatients who are also first pregnant and healthy in the past but had no hard -drinking history as the comparative group（B group）. Then observed the applied effect and bad reaction on the patients of the two groups when using propofol during painless induced abortion. Results The average dosage of propofol in group A was more than group B, while the applied effect was worse than group B and the bad reaction occurrence rate was higher than group B. Conclusion Patients with hard -drinking history have certain resistance to propofol in painless induced abortion.