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骨髓增生异常综合征转化成急性白血病联合化疗的疗效 被引量:4

COMBINATION CHEMOTHERAPY FOR ACUTE LEUKEMIA TRANSFERED FROM MYELODYSPLASTIC SYNDROME
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摘要 对16例由骨髓增生异常综合征转化成的急性白血病给予联合方案化疗。同时以16例病前无骨髓增生异常综合征病史的急性白血病为对照。转白组CR5例,CR率为31.3%,对照组CR12例,CR率为75%,二组比较有显著差异性(P<0.05),在化疗后下一疗程化疗前转白组的白细胞恢复低于3×109/L有8例,对照组2例,二组比较有显著差异(P<0.05)。生存曲线显示对照组的生存率高于转白组(P<0.05)。 Sixteen paitents with acute leukemia transfered from myelodysplastic syndrome treated by combined chemotherapy. And compared with 16 acute leukemia patients without MDS history. The complete remisson rate in the former were 31.3%, but in the controls were 75%. The CR rate in the former group was lower than that of the control group (P<0 05). Before the next chemotherapy the white cell counts lower than 3×10 9/L occured in 8 cases of the former group but 2 cases in the control group (P<0 05). The survival time in the control group was significantly higher than that of the former gruop (P<0 05).
出处 《白血病》 1997年第1期14-16,共3页
关键词 骨髓增生异常 综合征 急性 白血病 化疗 Myelodysplastic syndrome Acute leukemia Chemotherapy
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