多发伤后全身炎症反应综合征和多器官功能障碍综合征临床分析

Clinical study on systemic inflammatory response syndrome and multiple organ dysfunction syndrome after multiple trauma

目的提高对多发伤后并发全身炎症反应综合征（SIRS）和多器官功能障碍综合征（MODS）的认识。方法选取多发伤患者105例,分为SIRS组和非SIRS组,比较两组的MODS发生率及病死率。再根据SIRS严重程度分组,分析多发伤后SIRS和MODS发生的关系。结果多发伤后有较高的SIRS发生率,SIRS组MODS发生率和病死率均明显高于非SIRS组（P〈0.05）。随着SIRS严重程度的增加MODS发生率也增高（P〈0.05）。结论多发伤SIRS到MODS是一个临床常见的渐进过程,早期发现SIRS对多发伤预后的判断和治疗有重要意义。

Objective To study the significance of systemic inflammatory response syndrome（SIRS） and mulitiple organ dysfunction syndrome（MODS） after multiple trauma.Methods One hundred and five patients were divided into systemic inflammatory response syndrome（SIRS） group and non-SIRS group.The mortality rates and the incidence rates of MODS of SIRS group were compared with that of non-SIRS group.Patients with SIRS were divided into three groups according to the severity of SIRS.The relationship between SIRS and MODS was observed.Results SIRS occurrence was high after multiple trauma.The mortality rates of SIRS group were significantly higher than non-SIRS group（P〈0.05）.When the severity of SIRS increased,the incidence rates of MODS increased（P〈0.05）.Conclusion From multiple trauma to SIRS and MODS is one of the clinical common processes advanced gradually.To discover SIRS early is important to treatment and prognosis of the multiple trauma patients.