高血压病人药物治疗期间动态血压变化

Ambulatory Blood Pressure Monitoring in Antihypertensive Drug Treatmen

目的评价高血压病人药物治疗期间２４ｈ动态血压变化。方法２６例住院的高血压病人经药物治疗４周连续３ｄ随测血压，血压正常后进入本研究。治疗前后进行２４ｈ动态血压监测。结果患者随测血压（８～９ＡＭ，３～４ＰＭ）血压恢复到正常水平，但动态血压显示在一段时间内（６～８ＡＭ，６～１１ＰＭ）平均收缩和舒张压仍明显高于正常人平均水平（Ｐ＜０．０１），而该时间段易被临床医生忽视。结论随测血压不能实际全面反映高血压病人药物治疗的疗效，２４ｈ动态血压的监测可以正确评价高血压病人药物治疗的效果并根据高血压分布的时间来调整降压药的种类和剂量。

Aim\ To evaluate during drug treatment period the changes of blood pressure in 24 hours course.\ Methods\ Twenty two hypertensive patients were monitoring with ABPM during the four weeks captopril and metoprololum treatment.\ Results\ When casual blood pressure retuned normal in 8￣9 AM and 3￣4 PM, the ABPM showed abnormal in 6￣8 AM and 6￣11 PM.\ The abnormal BP in period of 6￣8 AM and 6￣11 PM alsways not detected by ordinally casual BP test.\ Conclusion\ ABPM may be used for evaluating the effects of drug treatment and adjusting the drug type and exact taking time.