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静脉滴注呋塞米治疗难治性充血性心力衰竭的疗效观察

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摘要 目的观察呋塞米(速尿)维持静脉滴注(静滴)治疗难治性充血性心力衰竭(CHF)的短期疗效。方法将经常规抗CHF治疗加分次静脉注射注(静滴)速尿300mg/d～400mg/d利尿效果差的34例患者,先静注速尿"负荷量",然后静脉滴注(静滴)速尿(≥1.5mg/min)维持,至尿量达≥2000ml即停止静滴,观察其每日利尿效应;治疗过程中适当补充电解质成分。结果维持静滴速尿治疗后尿量较治疗前均明显增加(P<0.01);其速尿用量第1d～3d较维持静点前用量明显增大(第1￣2天P<0.01,第3天则,P<0.05);静点治疗后体重、心率有较显著下降(P<0.01),血压有所下降(P>0.05);治疗后电解质无明显改变(P>0.05),治疗后血Cr明显降低(P<0.05),治疗3d～5d后所有患者临床症状和体征均明显改善。结论在常规抗CHF措施治疗下加用较大剂量(≥1.5mg/min)速尿维持静滴(≥5h/d)治疗难治性CHF是一种安全有效的方法。
作者 袁绍伦 王俊岭 董福生 李志仙 杨红磊 郭小雨
机构地区 河北省保定市第七医院心内科 河北省保定市解放军第二五二医院心内科
出处 《实用心脑肺血管病杂志》 2007年第9期676-678,共3页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词 心力衰竭 充血性 呋塞米 静脉滴注
分类号 R541.61 [医药卫生—心血管疾病]
  • 相关文献

参考文献7

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二级参考文献15

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实用心脑肺血管病杂志
2007年 第9期

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