摘要
趋化因子(chemokines)是一类一级结构相似,对白细胞具有化学趋化作用等多种生物学效应的小分子蛋白,在机体的防御和炎症反应等方面起着重要的调节作用。近年来许多研究发现,趋化因子在牙周炎的免疫发病机制中发挥着重要作用。深入研究趋化因子和牙周炎的关系,对牙周炎的预防、诊断、治疗以及治疗后疗效监测有重要意义。
The chemokines are a kind of small proteins with similar primary structures, which have various biological effect, mostly include chemotaxis of leukocyte, and play a significant regulating effect on the defense and the inflanunatory reaction of the body. In recent years, a lot of researches have found that the ehemokines play an important role in the immunopathogenesis of periodontitis. Therefore it is important to study the relation of chemokines and periodontitis for prevention, diagnosis, treatment and monitoring of curative effect of periodontitis.
出处
《国际口腔医学杂志》
CAS
2007年第6期424-426,共3页
International Journal of Stomatology
关键词
牙周炎
趋化因子
免疫机制
periodantitis
chemokines
immune mechanism