射频消融治疗悬雍垂腭咽成形术后无效的阻塞性睡眠呼吸暂停低通气综合征

Therapeutic effect of radiofrequency ablation on ineffective obstructive sleep apnea-hypopnea syndrome after uvulopalatopharyngoplasty

目的探讨等离子低温射频消融(radiofrequency ablation,RFA)治疗悬雍垂腭咽成形术(uvulopal-atopharyngoplasty,UPPP)术后无效的阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syn-drome,OSAHS)的疗效。方法选择39例UPPP术后无效的OSAHS患者接受RFA治疗。比较治疗前后呼吸暂停低通气指数(AHI)、最低血氧饱和度(LSaO2)、鼾声评级和Epworth嗜睡程度评分,评价治疗效果。结果治疗总有效率53.8%,患者治疗8周后鼾声评级的降低较治疗前无显著差异(P>0.05),Epworth嗜睡程度评分较治疗前明显降低(P<0.01)。治疗后6个月AHI较治疗前明显减低(P<0.05),LSaO2较治疗前明显升高(P<0.05)。结论对UPPP术后无效的OSAHS,RFA是一种有效的补救性治疗方法。

Objective To investigate the therapeutic effect of radiofrequency ablation （RFA） on ineffective obstructive sleep apnea-hypopnea syndrome （OSAHS） after uvulopalatopharyngoplasty （UPPP）. Methods RFA was performed to 39 OSAHS patients who were ineffective after UPPP. Such parameters as apnea-hypopnea index （AHI）, the lowest saturation of blood oxygen （LSaO2）, snoring scale, and the Epworth sleepiness scale preoperation were compared with those after operation to value the therapeutic effect of RFA. Results Eight weeks after RFA, the effective ratio was 53. 8% and the Epworth sleepiness scale decreased significantly （ P〈0. 01）, but no significant difference in snoring scale. Six months after operation, LSaO2 was improved （ P〈0. 05） and AHI decreased significantly （ P〈0.05）. Conclusion RFA is an effective remediational treatment for OSAHS patients ineffective to UPPP.