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Olmsted综合征一例 被引量:2

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摘要 患儿男,3.5岁。因双足趾、口周、外耳道角化性斑块3年.双手指,犬角化性斑块2年余,并瘙痒和疼痛入院治疗。半岁时.无明显诱因双足跖部出现黄豆大小黄褐色角化性斑块,双侧外耳道及口周出现褐红色斑块,皲裂,脱屑。一岁半时,舣手拇指第2指节出现黄色角化性斑块,伴瘙痒,夜间和病情活动时疼痛,按湿疹、掌跖角化症等治疗,外用维A酸、尿素软膏等疗效不佳。就诊10个月前患儿感冒后.病情进行性加重:患儿系二胎,足月顺产,对多种药物过敏,父母非近亲结婚。家族中无类似疾病。
出处 《中华皮肤科杂志》 CAS CSCD 北大核心 2007年第11期715-715,共1页 Chinese Journal of Dermatology
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  • 1马东来,胡瑾,方凯.Olmsted综合征国内首报[J].临床皮肤科杂志,2006,35(10):637-639. 被引量:8
  • 2Atherton DJ, Sutton C, Jones BM. Mutilating palmoplantar kerato- derma with periorificial keratotic plaques (Olmsted's syndrome). Br J Dermatol, 1990, 122(2): 245-252.
  • 3Rivers JK, Duke EE, Justus DW. Etretinate: management of keratoma hereditaria mutilans in four family members. J Am Acad Dermatol, 1985, 13(1 ): 43-49.
  • 4Cambiaghi S, Tadini G, Barbareschi M, et al. Olmsted syndrome in twins. Arch Dermatol, 1995, 131(6): 738-739.
  • 5Larregue M, Callot V, Kanitakis J, et al. Olmsted syndrome: report of two new cases and literature review. J Dermatol, 2000, 27(9): 557-568.
  • 6Inamadar AC, Palit A, Athanikar SB, et al. What syndrome is this? Olmsted syndrome. Pediatr Dermatol, 2004, 21 (5): 603-605.
  • 7Yoshizaki Y, Kanki H, Ueda T, et al. A further case of plantar squamous cell carcinoma arising in Olmsted syndrome. Br J Dermatol, 2001, 145(4): 685-686.
  • 8INAMADAR AC,PALIT A,ATHANIKAR SB,et al. What syndarome is this? Olmsted syndrome [ J]. Pediatr Dermatol, 2004,21 ( 5 ) : 603 - 605.
  • 9REQUENA L, MANZARBEITIA F, MORENC C, et al. Olmsted syndrome : report of a case with study of the cellular proliferation in Keratoderma [ J]. Am J Dermatopathol,2001,23 (2) :514 - 520.
  • 10KRESS DW,SERALY MP,FALO L,et al. Olmsted syndrme. Case report and identification of a Keratin 'abnormality[ J]. Arch Dermatol, 1996,132 ( 7 ) :797 - 800.

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