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疣状表皮发育不良继发鳞状细胞癌 被引量:2

Epidermodysplasia verruciformis with recurrent squamous cell carcinoma
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摘要 报告1例疣状表皮发育不良继发鳞状细胞癌。患者男,33岁。全身泛发扁平疣状皮损10年,鼻部复发性溃疡9个月。皮肤科检查:全身密集扁平疣状丘疹;鼻部一3cm×4cm的移植皮瓣,左侧鼻翼上方有一约1.5cm×2cm溃疡。皮损组织病理检查示棘细胞层上部见空泡化细胞伴少量角化不良细胞;真皮内有团块状细胞,灶内可见较多核大异形的鳞状细胞。 One case of epidermodysplasia verruciformis with recurrent squamous cell carcinoma is reported. The patient presented with generalized flat verrucous eruptions for 10 years with recurrent ulcers on the nose for 9 months. Flat verrucous papules were seen all over the body, and a 1.5 cm × 2 cm ulcer on the left part of the nose. Histopathology of the skin biopsy demonstrated that ballooning degeneration could be seen in the upper part of the stratum spinosum and undifferentiated squamous cell with large nucleus in the dermis.
出处 《临床皮肤科杂志》 CAS CSCD 北大核心 2007年第11期715-716,共2页 Journal of Clinical Dermatology
关键词 表皮发育不良 疣状 鳞状细胞 epidermodysplasia verruciformis carcinoma, squamous cell
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参考文献4

  • 1Roncalli de Oliveira W, Neto CF, Rady PL, et al. Seborrheic Keratosis-like lesions in patients with epidermodysplasia verruciformis[J]. J Dermatol, 2003, 30(1): 48-53.
  • 2de Oliveira WR, Festa Neto C, Rady PL, et al. Clinical aspects of epidermodysplasia verruciformis [J]. J Eur Acad Dermatol Venereol, 2003, 17(4): 394-398.
  • 3Oliveira WR, Rady PL, Festa C, et al. Skin cancer in epidermodysplasia verruciformis patients from Brazil [J]. J Eur Acad Dermatol Venereol, 2006, 20(9): 1154-1156.
  • 4郑艳红,马东来.疣状表皮发育不良继发基底鳞状细胞癌和多发性纤维毛囊瘤1例[J].临床皮肤科杂志,2003,32(9):530-531. 被引量:3

二级参考文献1

  • 1[1]Padlewska K, Ramoz N, Cassonnet P, et al. Mutation and abnormal expression of the p53 gene in the viral skin carcinogenesis of epidermodysplasia verrueiformis[J]. J Invest Dermatol, 2001,117(4): 935-942.

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