摘要
以博来霉素（国产名平阳霉素）１次气管内灌注造成大鼠急性肺损伤，观察当归注射液对其预防作用。结果表明：当归能显著减轻肺泡炎的程度（Ｐ＜０．０１），减少肺部炎症介质的分泌，抑制丙二醛的产生（Ｐ＜０．００１）。其机制可能为调节免疫、直接清除氧自由基及活血化瘀，改善微循环。
Our study shows that effects of angelica sinensis can prevent bleomycininduced acute injury in rats lungs. Angelica Sinensis can obviously reduce the alveolitis ( P <0.01),decrerase the excretion of inflammatory factors, and inhibit production of malondialdehyde ( P <0.001). Its effects may regulate immunity, clear free oxyradicals and ameliorated microcirculation
关键词
当归
肺损伤
急性
博来霉素
毒性
预防
plants, medicinal
angelica sinensis/PD
bleomycins/TO
alveolitis, extuinsic allergic/PC.
