摘要
目的探讨2型糖尿病患者血液流变学改变与糖尿病足(DF)的关系。方法把126例糖尿病患者分为DF组和非糖尿病足(NDF)组,测定全血黏度、血浆黏度、血细胞比容、血沉、纤维蛋白原。结果①年龄大,病程长,合并糖尿病性肾病、神经病变、视网膜病变、周围血管病变的糖尿病患者,DF发生率高;②DF组全血黏度(高切)、血浆黏度、血细胞比容、血沉、纤维蛋白原均有显著意义的升高(P均<0.05);③踝肱指数(ABI)异常组血液流变学参数较ABI正常组均有显著意义的升高(P均<0.05)。结论血液流变学异常能加重糖尿病的微循环障碍,促使DF的发生,有效地控制高黏状态,对防治DF有重要意义。
Objective To study the relationship between diabetic foot （DF） and the change of blood fluidity. Methods The blood viscosity,plasma viscosity,hematocrit,erythrocyte sedimentation rate,fibrinogen were determined in 126 type 2 diabetes cases. They were divided into DF group and non - diabetic foot （NDF） group. Results （1）The incidence of DF is higher in older and longer course of diabetes cases with renalpathy,neuropathy,peripheral artery disease and retinopathy. （2） The blood viscosity,plasma viscosity,hematocrit,erythrocyte sedimentation rate and fibrinogen are significantly higher in DF group. （3） The indexes of blood fluidity are significantly higher in Ankle Brachial Index（ABI） abnormal group than normal group. Conclusions To have the blood fluidity under control effectively is very important for prevention and treatment of DF.
出处
《医学研究杂志》
2007年第11期71-73,共3页
Journal of Medical Research
关键词
糖尿病
糖尿病足
踝肱指数
血液流变学
Diabetes mellitus
Diabetic foot
Ankle brachial index
Blood fluidity
