河南省农村地区胃癌危险因素的病例对照家系研究

A case-control family study of gastric cancer in Henan province

目的:探讨河南农村地区胃癌发生的危险因素。方法:确定胃癌病例家系和对照家系各325户,每组1010人,以家庭为单位入户面访方式收集人群资料。应用单因素和多因素非条件logistic回归分析探讨不同因素对胃癌发病的影响。结果:胃不适症状、暴饮暴食、口味重、吃剩饭>3次/周、精神刺激史等因素在病例家系与对照家系的分布中差异具有统计学意义。结论:胃不适症状、暴饮暴食、口味重、吃剩饭>3次/周、精神刺激史等因素是病例家系成员发生胃癌的危险因素。

Objective To explore the risk factors of gastric cancer in the rural area of Henan province. Methods Three hundred and twenty-five families with gastric cancer and 325 control families （1 010 persons in each group ） were selected among the rural residents in 4 counties of Henan province. Totally 2 020 people were surveyed and assessed using population-based case-con- trol family study. Results Gastric cancer was related to stomach upset, irregular dietary, hobby for salty taste, residual food, and history of mental stimulus. Conclusion Stomach upset, irregular dietary, hobby for salty taste, residual food, and history of mental stimulus are the risk factors of gastric cancer.