择期剖宫产预防性应用抗生素两种方法比较

Comparison of Two Methods of Administrating Antibiotics for Elective Caesarean Section

目的:探讨择期剖宫产术抗生素应用的理想时机和方法。方法:将83例择期剖宫产病例随机分为两组。实验组(n=41)采用围术期+术后2 d用药,对照组(n=42)采用常规方法术后序贯3 d用药;观察两组患者术后医学指标(平均体温、产褥病率、腹壁切口良好愈合情况)和经济学指标(人均抗生素用量、人均抗生素使用天数、人均抗生素使用费用及术后平均住院天数)。结果:两组患者术后的平均体温、腹壁切口良好愈合率及术后平均住院天数无统计学差异(P>0.05),但产褥病率及其余3项经济学指标,差异均具有统计学意义(P<0.05)。结论:择期剖宫产围术期+术后2 d抗生素应用方法预防感染临床效果好,经济方便,操作简单,值得推广。

Objective：To explore the optimization method of administrating antibiotics for elective caesarean section. Methods： Applied prospective study,divided 83 cases into 2 groups randomly. The patients in group Ⅰ received antibiotics during peri-operation and postoperation,while those in group Ⅱ received traditionally antibiotics during postoperation,compare the two groups indicatrixes of medicine and economics. Results：Mean body tempera K-ture, condition of cut agglutination and mean hospital days after operation were of no statistics difference in 2 groups,but puerperal morbidity,percapita dosage,days and cost of antibiotics usage were of statistical difference. Conclusion：The administration in group Ⅰ would be more benefit than that in group Ⅱ for cesarean section.