ω-3脂肪乳剂对腹部大手术患者预后的影响

The impact of ω-3 fish oil fat emulsion on the clinical outcome of the severe major abdomen operation

目的评价静脉应用ω-3脂肪乳剂对重症患者腹部手术预后的影响。方法以2006年1月至12月收治的32例腹部大手术并应用ω-3脂肪乳剂的患者为研究对象,以同期未应用ω-3脂肪乳剂的患者为对照,对其手术前后的实验室和临床资料进行回顾性分析。结果ω-3脂肪乳研究组与对照组患者的术后住院时间无明显差异,而感染的发生比例以及死亡率均低于对照组(P<0.05),术后第7天的实验室指标中,仅有血清TBIL,BUN和Cr低于对照组(P<0.05)。结论ω-3脂肪乳剂有利于腹部大手术患者术后的恢复,对于较严重腹部大手术患者,应尽量应用。

Objective To evaluate the effect of ω-3 ish oil fat emulsion applied on the outcomes of the severe major abdomen operation. Methods Thirty - two adult patients undergoing major abdomen operation and injection of ω-3fish oil fat emulsion from Jan. 2006 to Dee. 2006 were enrolled and their clinical and laboratory parameters before and after operation were compared to the other control 32 adult patients at the same time retrospectively. Results The post - operation infection rate and mortality rate in the experimental group were lower than in the control group （ P 〈 0.05）, and TBIL,BUN and Cr of the laboratory parameters in the experimental group were lower than in the control group （ P 〈 0.05） at 7th day after the operation. Conclusion ω-3fish oil fat emulsion acid supplementation is beneficial to the outcomes,and should be used conventionally for the severe major abdomen operation.