血定安对手术患者纤溶功能的影响

The effect of gelofusine on the fibrinolyticfunction in suraical patients

观察了２５例手术患者快速输注血定安（Ｇｅｌｏｆｕｓｉｎｃ）后血浆组织型纤溶酶原激活物（ｔ－ＰＡ）及其抑制物（ＰＡＩ）、Ｄ－二聚体、α－纤溶酶抑制物（α－ＰＩ）活性的变化情况。结果显示：输入血定安１０００ｍｌ后即刻、２ｈ．２４ｈ．对ｔ－ＰＡ．ＰＡＩ．Ｄ－二聚体、α２－ＰＩ活性均无明显影响，Ｐ均＞０．０５。表明血定安不影响手术患者纤溶系统功能。

The effect of intravenous, Gelofusine on plasma tissue-type plasminogen activator)t-PA_,plasminogenactivator inhibitor(PAI), D-Dimer and plasmin imhibitor was studied in 25 surgical patients underepidural anesthesia. Results showed that there was no significant difference of plasma levels of t-PA, PAI,D-Dimer and PI between pre-intravenous Gelofusine and immediately, 2 hours and 24 hours afterintravenous Gelofusine, The conclusion was that Gelofusine didn't influene surgical patients' fibrinolyticfunction.