亚甲蓝在肛肠病术后镇痛应用的临床研究

Clinical study of methylthioninium chloride on analgesia after anorectal diseases operation

目的:解决肛肠病术后疼痛问题。方法:以亚甲蓝为主,组成长效镇痛剂进行临床应用。观察镇痛治疗的满意度,生理指标,术后不良反应。结果:Ⅰ度疼痛达到61.57%,Ⅱ度疼痛达到28.23%,Ⅲ度疼痛达到10.2%;排便不畅以混合痔偏多,达到39%。结论:亚甲蓝长效镇痛剂用于肛肠病术后疼痛效果满意,但浓度不超过33%,一次用量不超过1ml。实施镇痛时注意加强监测预防和及时处理不良反应和并发症。

Objective：Post-operative analgesia of anorectal diseases was investigated in the study.Methods：The patients who had undergone anorectal operations received long-acting methylthioninium chloride compound.The indexes for evaluation included pain extents ,physical aspects ,postoperative adverse reactions and complications.Results：The analgesic efficacy was adopted.There was 61.57% whose pain reached Ⅰ grade after anorectal operation, 28.23% whose reaching Ⅱgrade,10.2% whose reaching Ⅲgrade.But the hard defecation was more than other groups on the mixed hemorrhoids which was 39%.Conclusion： It is concluded that the long-acting cethylthioninium chloride compound is better in terms of efficacy.h is suggested that the concentration of cethylthioninium chloride should not be more than 33% ,and that the dosage of local injection should not be more than 1 ml.The attention should be taken in the aspects of nursing, prevention of adverse reaction and complications.