期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

丙酮酸脱羧酶的催化机制及应用研究进展 被引量：2

Progress on the Catalytic Mechanism of Pyruvate Decarboxylase and Its Application
下载PDF
导出
摘要 综述了丙酮酸脱羧酶的结构及催化机理,并介绍了其在酒精生产、药物合成和有机合成方面的应用。 The structure and catalytic mechanism of pyruvate decarboxylase wre reviewed, and the application of pyruvate decarboxylase in ethanol fermentaion,drug synthesis and organic synthesis were introduced.
作者 段文凯 吕美巧 江蕾 周晓云
机构地区 浙江工业大学生物与环境工程学院
出处 《科技通报》 2007年第6期816-819,共4页 Bulletin of Science and Technology
基金 浙江省科技厅重点资助项目(2004C21005)
关键词 丙酮酸脱羧酶 结构 催化机理 应用 pyruvate decarboxylase structure catalytic mechanism application
分类号 Q814 [生物学—生物工程]
  • 相关文献

参考文献22

  • 1Heike B, Martina P,Joachim G, et al. The replacement of Trp392 by alanine influences the decarboxylase/ carboligase activity and stability of pyruvate decarboxylase from Zymomonas mobilis [J]. Eur J Biochem ,1995,234:650 - 655.
  • 2姚尧,李继珩.丙酮酸脱羧酶催化合成L-苯基乙酰基甲醇的研究[J].中国药科大学学报,1999,30(2):115-118. 被引量：5
  • 3Rogers P L , Shin H S, Wang B. Biotransformation for L-ephedrine production[J]. Advances in Biochemical Engineering ,1997,56:33 - 59.
  • 4蒋雅红,游松.丙酮酸脱羧酶及其在手性合成中的应用[J].中国药物化学杂志,2002,12(2):113-118. 被引量：3
  • 5Judith M C , Ronald G D. Structure and properties of pyruvate decarboxylase and site-directed mutagenesis of the Zymomonas mobilis enzyme [J]. Biochimica Biophysica Acta, 1998,1385:323 - 326.
  • 6Dyda F , Furey W , Swaminathan S , et al. Catalytic centers in the thiamin diphosphate dependent enzyme pyruvate decarboxylase at 2. 4 resolution [J]. Biochemistry, 1993,32 :6165 - 6170.
  • 7Arjunan P ,Umland T ,Dyda F, et al. Crystal structure of the vthiamin diphosphate-dependent enzymepyruvate decarboxylase from the yeast Saccharomyces cerevisiae at 2. 3 ,A resolution[J]. J Mol Biol, 1996, 256 :590-600.
  • 8Hubner G , Tittmann K , Killenberg Jabs, etal. Activation of thiamin diphosphate in enzymes[J]. Biochim. Biophys. Acta, 1998,1385 : 221 - 228.
  • 9Dobritzsch, D, Konig S , Schneider G, et al. Highresolution crystal structure of pyruvate decarboxylase from Zymomonas mobilis. Implications for substrate activation in pyruvate decarboxylase [ J ]. J Biol. Chem, 1998,273:20196 - 20204.
  • 10Breslow, R. On the mechanism of thiamine action. IV. ^1 Evidence from studies on model systems[J]. J. Am. Chem. Soc. , 1958, 80:3719-3726.

二级参考文献33

  • 1胡卓逸 厉滔 等.考马斯亮兰G-250染料测定蛋白质方法的改进[J].中国药科大学学报,1987,18:133-133.
  • 2[1]Heike B,Martina P,Joachim G,et al.The replacement of Trp392 by alanine influences the decarboxylase/carboligase activity and stability of pyruvate decarboxylase from Zymomonas mobilis[J].Eur J Biochem,1995,234:650-655.
  • 3[2]Fuganti C,Grasselli P.Synthesis of the C14 chromanyl moietyl of nature α-tocopherol(vitamin E)[J].J Chem Soc Chem Commun,1982,4:205-206.
  • 4[3]Gala D,Dibedetto DG,Clark JE,et al.Preparation of antifungal Sch42427/SM9164:preparative chromatographic resolution,and total asymmetric synthesis via enzyme preparation of chiral hydroxy arylketones[J].Tetrahedron Lett,1996,37:611-614.
  • 5[4]Hyon SS,Peter LR.Production of L-phenylacetylcarbinol from benzaldehyde using partially purified pyruvate decarboxylase[J].Biotechnol Bioeng,1996,49:52-62.
  • 6[5]Naoki M,Shigeki H,Takeshi S,et al.Improved conditions for the production and characterization of 1-arylpropane-1,2-diols and related compounds[J].Biosci Biotech Biochem,1995,59:2282-2291.
  • 7[6]Kren V,Crout DHG,Dalton H,et al.Pyruvate decarboxylase:a new enzyme for the production of acyloins by biotransformation[J].J Chem Soc Chem Commun,1993.341-343.
  • 8[7]Crout DHG,Davis S,Heath RJ,et al.Application of hydrolytic and decarboxylating enzymes in biotransformation[J].Biocatalysis,1994,9:1-30.
  • 9[8]Judith MC,Ronald GD.Structure and properties of pyruvate decarboxylase and site-directed mutagenesis of the Zymomonas mobilis enzyme[J].Biochimica Biophysica Acta,1998,1385:323-338.
  • 10[9]Dyda F,Furey W,Swaminathan S,et al.Catalytic centers in the thiamin diphosphate dependent enzyme pyruvate decarboxylase at 2.4? resolution[J].Biochemistry,1993,32:6165-6170.

共引文献4

同被引文献48

  • 1廖文彬,崔百明,温玮,彭明.赤霉素负调控因子GhRGL(RGL-LIKE)基因序列与功能预测分析[J].热带作物学报,2009,30(2):170-175. 被引量：5
  • 2杨霄,崔志峰.酵母生物转化生产2-苯乙醇的研究进展[J].应用与环境生物学报,2006,12(1):140-144. 被引量：28
  • 3宋浩雷,郭晓贤,杨月梅,江贤章,黄建忠.酿酒酵母ADH3基因的敲除[J].工业微生物,2006,36(4):28-32. 被引量：9
  • 4Etschmann M M,Bluemke W,Sell D. Biotechnological production of 2-phenylethanol[J].{H}Applied Microbiology and Biotechnology,2002,(1):1-8.
  • 5Styger G,Prior B,Bauer F F. Wine flavor and aroma[J].{H}Journal of Industrial Microbiology and Biotechnology,2011,(9):1145-1159.
  • 6Ehrlich F. (U)ber das nattrliche Isomere des Leucins[J].Berichte der Deutschen Chemischen Gesellschaft,1907,(2):2538-2562.
  • 7Romagnoli G,Luttik M A,K 0 Tter P. Substrate Specificity of Thiamine Pyrophosphate-Dependent 2-Oxo-Acid Decarboxylases in Saccharomyces cerevisiae[J].{H}APPLIED AND ENVIRONMENTAL MICROBIOLOGY,2012,(21):7538-7548.
  • 8Stark D,Munch T,Sonnleitner B. Extractive bioconversion of 2-phenylethanol from L-phenylalanine by Saccharomyces cerevisiae[J].{H}Biotecnology Progress,2002,(3):514-523.
  • 9Hazelwood L A,Daran J M,van Maris A J. The Ehrlich pathway for fusel alcohol production:a century of research on Saccharomyces cerevisiae metabolism[J].{H}APPLIED AND ENVIRONMENTAL MICROBIOLOGY,2008,(8):2259-2266.
  • 10Iraqui I,Vissers S,Cartiaux M. Characterisation of Saccharomyces cerevisiae ARO8 and ARO9 genes encoding aromatic aminotransferases I and Ⅱ reveals a new aminotransferase subfamily[J].{H}Molecular and General Genetics,1998,(2):238-248.

引证文献2

二级引证文献13

科技通报
2007年 第6期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部