摘要
甲状腺激素应答蛋白基因Spot14已被证实在脂肪合成过程中有着重要的作用,主要表现在对ATP柠檬酸酶、脂肪酸合成酶和苹果酸酶等脂肪合成酶基因表达的调控作用。简要综述了Spot14基因在动物脂肪合成方面的最新研究进展,并提示对Spot14基因的深入研究将有助于阐明机体脂肪沉积的规律.
Spot 14 gene has been identified to play a role in lipogenesis and regulate the transcription of enzymes related with de novo lipogenesis in liver, i.e., ATP-citrate lyase (ACLY), fatty acid synthase (FAS) and malie enzyme (ME). In this review, authors present the recent advances in research on the effects of Spot 14 or THRSP gene in animal lipogenesis, and suggest that further study in Spot 14 gene may help to illustrate the mechanism of fat deposition deeply.
出处
《韶关学院学报》
2007年第3期110-113,共4页
Journal of Shaoguan University