黑加仑籽油降血脂功能性的研究

Study on Efficiency of Regulating Blood Lipids of Blackcurrant Seed Oil in Hyperlipidemia Rats

目的:考察黑加仑籽油在大鼠形成高血脂症过程中对血脂的影响。方法:采用40只雄性Wistar大鼠作为实验动物,随机分为4组:空白组、高脂组、高剂量组、低剂量组。测定大鼠血清中甘油三酯(TG)、总胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、动脉硬化指数(AI)以及大鼠体重在实验前后的变化。结果:低剂量组和高剂量组大鼠的TG、TC和AI值均不同程度低于高脂组,而HDL-C却极显著高于高脂组(p<0.01)。结论:黑加仑籽油能够显著降低高血脂症大鼠血清中TG和TC的含量以及AI值,并可有效抑制HDL-C含量的降低,具有显著的降血脂功效。

Objective： To study the influence of blackcurrant seed oil on serum lipid level in hyperlipidemia rats. Methods： Forty male Wistar rats were divided into four groups randomly： control group, hyperlipidemia model group, high-dose group and lowdose group. The concentration of serum triglyceride（TG）, cholesterol（TC）, high-density lipoprotein （HDL-C） and arteriosclerosis indes（AI） were assayed after 21 days. Results： The levels of TG, TC and AI in high-dose group and low-dose group were obviously lower than that in hyperlipidemia model group, while the level of HDL-C in high-dose group and low-dose groups was much higher than that in hyperlipidemia model group. Conclusion： The results showed that blackcurrant seed oil had the function of reducing serum lipid level obviously.