人乳头瘤病毒型别及其相关疾病

Human Papillomavirus Types and Their Related Diseases

随着现代分子生物学技术的发展,科学家们发现越来越多的人乳头瘤病毒(HPV)亚型与多种不同疾病相关。高危型HPV16、18、31、33、45、52和61等是子宫颈、外阴、阴道、阴茎、肛门和口腔以及口咽癌的病因,低危型HPV6和11是生殖器疣的病因。HPV与喉癌有一定病因学联系,然而与食管癌和肺癌的关系尚不能确定。

With the development of biomolecular technology, more human papillomavirus （HPV） types have been found to be related with various diseases. High-risk HPV 16, 18, 31, 33, 45, 52, and 61 have shown causal relationship with cancers of the cervix, vulva, vagina, penis, anus, oral cavity, and oropharynx, low-risk HPV 6 and 11 have shown causal relationship with genital warts. HPV may also cause cancer of the larynx. However, the relationships between HPV and esophagus and lung cancers are still controversial.