摘要
用特殊的高分子微球粘接技术制备成型用模板,通过注浆成型制备出孔结构可控的球形多孔羟基磷灰石(hydroxyapatite, HA)支架。重点研究了 HA 支架的制备工艺参数对孔结构的影响及孔结构和力学性能之间的关系。结果表明:加入合适粒径的氯化钠(NaCl)填充剂可调节支架的孔隙率和连通性。通过改变高分子微球的尺寸和 NaCl 晶体的添加量,支架的孔径在 100～800 μm范围内、孔隙率在 40%～90%范围内实现可控。研究了多孔HA 支架的压缩强度(σ)与孔隙率(p)之间的定量关系,为多孔 HA 支架强度的预测提供了依据。
Spherical porous hydroxyapatite （HA） scaffold was fabricated via a casting process with a polymer template. The influences of the preparation process on the pore characteristics and mechanical properties were investigated. The results shown that the intercon- nectivity and porosity of scaffold were improved by adding NaC1 of different particle diameters. The pore size of scaffold was varied between 100/am and 800/am and the porosity was between 40% and 90%, by adjusting the size of the polymer spheres and the content of the NaC1 particles. Besides, the relationship between compressive strength and porosity was determined, and thus the compressive strength could be predicted.
出处
《硅酸盐学报》
EI
CAS
CSCD
北大核心
2007年第9期1205-1209,共5页
Journal of The Chinese Ceramic Society
关键词
羟基磷灰石
球形孔
孔径
孔隙率
压缩强度
hydroxyapatite
spherical pore
pore size
porosity
compressive strength
