小儿腹腔镜肾上腺切除术对IL-6、内皮素和C反应蛋白水平的影响

The Influence of Laparoscopy Adrenalectomy(LA) and Open Adrenalectomy(OA) on the Contents of IL-6,C-Reactive Protein and Endothelin in Children

目的:探讨小儿开腹肾上腺切除术与腹腔镜肾上腺切除术两种方法对患儿血IL-6、C反应蛋白水平和内皮素水平的影响,从而比较两种术式对患儿手术应激的影响程度。方法:选择开腹肾上腺切除术患儿25例,腹腔镜肾上腺切除术患儿17例,分别于术前和术后抽取静脉血检测血IL-6、C反应蛋白和内皮素的水平并进行比较。同时比较两组手术时间、术中出血量及术后住院时间。结果:开放手术组患儿术后血IL-6、C反应蛋白和内皮素的水平明显高于腹腔镜手术组,而术前两组间无统计学差异。腹腔镜组患儿手术时间术中出血量及住院时间均小于后者。结论:腹腔镜肾上腺切除术与开腹肾上腺切除术相比,手术刺激小,恢复快。

Objective： To study the effect of laparoscopy adrenalectomy and open adrenalectomy on the plasma contents of IL-6, C-reactive protein（CRP） and endothelin （ET） in child patients. Mathods： The concemtrations of IL-6, CRP and ET were determined in the blood samples before and after operation in patients undergoing OA（n=25） and patients undergoing LA（n=17）. And the datas were compared between the two groups. Results： All postoperation plasma IL-6, CRP and ET level in OA group were much higher than that in LA group. But there were no statistic difference in preoperation plasma IL-6, CRP and ET level between the two groups. Conclusion： La- paroscopy Adrenalectomy is more efficient and safer than Open Adrenalectomy for child patients.