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糖尿病患者HbA1c与空腹血糖联合测定的临床意义 被引量:3

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摘要 目的探讨糖尿病患者糖化血红蛋白(HbA1c)和空腹血糖(FPG)联合测定的临床意义。方法使用DREW-DS5全自动糖化血红蛋白分析仪检测HbA1c,HITACHI 7060全自动生化分析仪检测FPG,对其相关性进行分析。结果通过对227例门诊患者同时测定HbA1c和FPG,确诊了38例糖尿病患者。其中19例FPG正常,HbA1c异常,经OGTT或餐后2h血糖复查,最后确诊11例为Ⅱ型糖尿病患者;33例FPG和HbA1c均异常的患者,经OGTT或餐后2h血糖复查确诊27例糖尿病患者。38例确诊患者的平均血糖值与HbA1c密切相关,两者之间的关系为:HbA1c增加1%,平均血糖值增加1.33~1.61mmol/L,HbA1c与平均血糖值的最佳符合点在餐后2h,FPG的相关性最差。结论HbA-C对糖尿病的筛选较FPG有更高的敏感性,对糖尿病的诊断和长期血糖水平的监控和观察有重要意义,可作为轻症、Ⅱ型糖尿病的早期诊断指标。
出处 《国际检验医学杂志》 CAS 2007年第11期1045-1046,共2页 International Journal of Laboratory Medicine
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  • 1Tahara Y, Shima K. The responses of GHb to stepwise plasma glucose change over time in diabetic patients. Diabetes Care,1993,16:1313-1314.
  • 2Goldstein DE, Little RR, Wiedmeyer HM,et al. Glycohemoglobin testing in diabetes mellitus: assay methods and clinical interpretation. In: Vasselli JR, Maggio CA, Scriabine A, Eds. Drugs in Development. Vol 1. Branford, CT: Neva Press,1993.253-267.
  • 3Curt L,Jack D, Wiedmeyer HM, et al. Defining the relationship between plasma glucose and HbA1c. Diabetes Care,2002,25:275-278.
  • 4岛健二.糖化血红蛋白的标准化报告[J].糖尿病,1994,37:855-864.
  • 5后藤由夫.老人保险法手册·关于糖尿病检查[M]东京:日本医事新报社,1996.
  • 6Tahara Y,Shima K. Kinetics of HbAlc, glycated albumin, and fructosamine and analysis of their weight functions against plasma glucose level[J ]. Diabetes Care. 1995,18:440-447.
  • 7Goldstein DE. Glycated hemoglobin estimation in the 1990s: A review of assay methods and chinical interpretation [M]. The Diabetes Annual 18, Marshall SM, Home PD (ed), Elsevier,Amsterdam, 1994.19-212.
  • 8宫下撤夫.常规HbA1c测定仪用亲和梯度法检测异常血红蛋白[J].日本临床检查自动化学会会志,2002,27.
  • 9Krishnamurti U,Stelfes MW. Glycohemoglobin; a primary predictor of the development or reversal of complications of diabetes mellitus[ J ]. Clin Chem, 2001,47 : 1157-1165.
  • 10Kilpatrick ES. Glycated haemoglobm in the year 2000[J]. J Clin Pathol, 2000.53 : 335-339.

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  • 1周翔海,纪立农.空腹血糖和糖化血红蛋白用于筛查糖尿病的研究[J].中华糖尿病杂志(1006-6187),2005,13(3):203-205. 被引量:157
  • 2马博清,叶蔚,陈树春,魏立民,王智华,张文杰.老年2型糖尿病患者七时点血糖与糖化血红蛋白的相关性分析[J].中华老年医学杂志,2005,24(10):736-738. 被引量:4
  • 3邵泽伟,孟红.脂蛋白(a)与动脉粥样硬化和多种疾病的关系[J].国际检验医学杂志,2006,27(6):524-526. 被引量:11
  • 4Hoelzel W, Miedema K. Development of a reference system for the international standardization of HbAlc/glycohemoglobin determi nations[J]. J Int Fed Clin Chem, 1996,9 (2) : 62-67.
  • 5Genuth S, Alberti KG, Bennett P, et al. Follow-up report on the diagnosis of diabetes mellitus [ J ]. Diabetes Care, 2003,26 ( 11 ) 3160-3167.
  • 6Yamamoto-Honda R,Kitazato H,Hashimoto S. Distribution of blood glucose and the correlation between blood glucose and hemoglobin A1c levels in diabetic outpatients[J].Endocrine Journal,2008,(5):913-923.doi:10.1507/endocrj.K08E-071.
  • 7Pistrosch F,Koehler C,Wildbrett J. Relationship between diurnal glucose levels and HbA1c in type 2 diabetes[J].Hormone and Metabolic Research,2006.455-459.
  • 8Tomoko S,Akio O,Tomaya M. Relationship between clinical markers of glycemia and glucose excursion evaluate by continuous glucose monitoring(CGM)[J].Endocrine Journal,2010.135-140.
  • 9Roblfing CL,Wiedmeyer HM,Little RR. Defining the relationship between plasma glucose and HbA1c:analysis of glucose profiles and HbA1c in the Diabetes Control and Complications Trial[J].Diabetes Care,2002.275-278.
  • 10Avignon A,Radauceanu A,Monnier L. Nonfasting plasma glucose is a better marker of diabetic control than fasting plasma glucose in type 2 diabetes[J].Diabetes Care,1997.1822-1826.

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