肺部疾病中痰巨噬细胞对结核菌素试验反应的临床研究

Clinical Study on Reaction About Sputum Macrophage to Tuberculin Test of Pulmonary Patients

目的:测定肺结核、肺肿瘤及非特异性炎症患者注射结核菌素前后痰巨噬细胞的不同数量变化,由此提供一种新的鉴别诊断方法。方法:皮内注射结核菌素、收集注射前、后痰液,测定痰巨噬细胞在不同时间的数量变化。结果:肺结核病人在结核菌素试验后痰巨噬细胞明显增加,肺部肿瘤及非特异性炎症则无显著性变化。结论:肺部患者测定结核菌素前后痰巨噬细胞变化,可作为菌阴肺结核与肺部肿瘤及非特异性炎症鉴别诊断依据之一。

Objective:Before and after tuberculin injection,we detemfined the changes of the number of sputum macrophage to the patients of pulmonary tuberculosis,lung tumor and non-specific inflamma- tion.The purpose is to mare differential diagnosis methods.Methods:Subcutaneous injected tuberculin, and collected sputum about injection,determined the changes of the number of suptum macrophage in dif- ferent time.Resultes:The number of sputum macrophages of pulmonary tuberculosis patients were obvious- ly increas after tuberculin test.But no obvious changes were founded in lung cancer and non-specific in- flammatory patients.Conclusion:To determine the changes of sputum macrophage of pulmonary patients is one of the differential diagnosis methods to the bacteria positive cases,lung tumor and non-specific in- flammation patients.