反义ODN对人卵巢癌细胞株A2780 FSHR表达的影响
摘要
卵巢癌占妇科恶性肿瘤死亡率首位，常规治疗方法为手术和化疗，但生存率较低。大量研究显示，卵泡刺激素（Follicle stimulating hormone，FSH）对卵巢癌的发生发展具有明显促进作用。FSH生理作用的发挥是通过特异性G蛋白偶联受体（Folliclestimulating hormone receptor，FSHR）所介导。近年，FSHR在卵巢中的表达倍受关注。卵巢癌细胞有无FSHR过度表达，恶性与良性肿瘤细胞间FSHR表达差异等问题，目前尚不清楚。
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2007年第5期290-292,共3页
Chinese Journal of Clinical Oncology
基金
湖北省卫生厅科研基金资助(编号:JXIB002)
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