摘要
目的:探讨肝细胞性肝癌(HCC)的肝动脉化疗药物栓塞(TACE)联合三维适形放疗(3DCRT)的综合治疗效果.方法:原发性肝癌患者76例,进行前瞻性分组研究,综合治疗组40例行TACE结合3DCRT治疗,对照组36例单纯行TACE治疗.结果:综合治疗组1,2,3年生存率分别为78%,60%,34%;对照组分别为50%,32%,18%(P<0.05).结论:对不能手术切除治疗的原发性肝癌患者,TACE结合3DCRT治疗能明显提高治疗疗效,且无严重毒副作用.
AIM: To study the effect of transcatheter arterial chemoembolization (TACE) combined with three-dimensional conformal radiotherapy (3DCRT) on inoperable primary liver cancer, METHODS: Patients were prospectively randomized into a TACE + 3DCRT group (combined group, 40 patients) and a TACE therapy alone group (TACE group, 36 patients), RESULTS: The overall 1-, 2-and 3-year survival rate was 78%, 60% and 34% in the combined group, and 50%, 32% and 18% in the TACE group. The difference between the two groups was significant (P 〈 0.05). CONCLUSION: TACE + 3DCR is more effective than TACE therapy alone on inoperable primary liver cancer, without inflicting more treatmentrelated toxicity.
出处
《世界华人消化杂志》
CAS
北大核心
2007年第29期3140-3142,共3页
World Chinese Journal of Digestology
关键词
原发性肝癌
肝动脉化疗药物栓塞
三维适形放疗
Primary liver cancer
Transcatheter arterial chemoembolization
Three-dimensional conformal radiotherapy