调经助孕中药对排卵障碍性不孕者子宫内膜组织形态的影响

Effects of Chinese Medicines for Pregnancy Improve with Menstrual Regulation on Endometrial Eorphology of Infertile Women due to Ovulation Failure

目的:观察调经助孕中药对排卵障碍性不孕者子宫内膜组织形态学方面表现的影响。方法:服用中药25例,采用服用中药前后自身对照的方法,并分别于月经周期促黄体激素生成激素(LH)峰值的-2、+2、+7天进行子宫内膜活检取材,进行组织形态学的分析。结果:排卵障碍性不孕者中内膜组织形态异常者高达84.0%(21/25),中药治疗3个周期具有调经、促排卵、健内膜作用,同时子宫内膜形态学明显改善,促进内膜组织功能活跃旺盛,增殖活性和分泌活性显著增强趋于正常。结论:内膜感受态的协调改善是实现助孕作用的重要基础。

Objective ： To investigate the effects of Chinese medicines for pregnancy improve with menstrual regulation （ Tiaojing zhuyun） on endometrial morphology of infertile women due to ovulation failure. Methods： Self- control design was adopted to compare the endometrial histology before and after administration of medicines in 25 eases. Biopsies were obtained in days of LH -2, LH ＋ 2 and LH ＋ 7, respectively. Results： The endometria of infertile women with ovulation failure showed paramorphia which was accounted for 84.0% （21/25 ）. After three treatment cycles, the regularity of menstruation, ovulation and endometrial morphology were significantly improved, especially for proliferative and secretory activity of the endometrium. Conclusion： Improvement of endometrial receptivity provides a basis for effectivenesss of the medicine.