纳氏测氨法半定量诊断HP感染的方法及其应用

Effect of Solvents on Critical Concentration of Three Liquid Crystalline Cellulose Derivatives

对纳氏测氨法尿素酶试验（ＮＵＴ法）进行半定量标准化后，进一步建立了纳氏测氨半定量诊断人胃粘膜中幽门螺杆幽（ＨＰ）感染程度的方法，使ＮＵＴ法可同时用于定性及半定量诊断ＨＰ感染及感染程度．对经过半定量检测的３５０例患者作分析，显示轻、中、重度感染比率分别为５４．６％、３４．０％及１１．４％，另对其中１８２例慢性浅表性胃炎进行病变程度与ＨＰ感染程度的相关性分析，表明慢性浅表性胃炎的病变程度与ＨＰ的感染程度呈明确的正相关性（ｐ＜０．０５），提示胃部疾病的恶性演变尚与感染程度有关．

Critical concentrations of lyotropic liquid crystalline ethylcellulose, hydroxypropy1 methy1 cellulose and diacetate cellulose in more than ten solvents were determined by using polarized microscopy.In general, there was a tendency that the more the solubility parameter of solvents close to that of polymer, the lower the critical concentration was, although the experimental points were somewhat dispersed. When the sort of solvents was limited to a simple series such as acetic acid,chloroacetic acid, dichloroacetic acid and trichloroacetic acid, a good linear relation was found between critical concentration and solubility parameter.