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重组人角质细胞生长因子对小鼠口腔黏膜炎的防护作用 被引量：1

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摘要 头颈部恶性肿瘤患者常规放疗口腔黏膜炎发病率高达97％，而行超分割放疗发病率则高达100％。严重的口腔黏膜炎可造成放疗中断，而肿瘤细胞可能在中断期间发生加速再增殖，影响肿瘤治疗效果。重组人角质细胞生长因子（rhKGF）为生物制品，由成都生物制品公司提供，是内源性的人KGF的剪切版本，剪切版的非糖基化的蛋白质被证明与内源性的KGF对KGFR产生相同的活性。
作者 丁晓燕 王庆国 何新勇 李雅钢 高献书
机构地区 北京大学第一医院放疗科
出处 《中华放射肿瘤学杂志》 CSCD 北大核心 2007年第6期482-483,共2页 Chinese Journal of Radiation Oncology
关键词 重组人角质细胞生长因子 口腔黏膜炎 防护作用 恶性肿瘤患者 小鼠 常规放疗 生物制品 超分割放疗
分类号 R739.91 [医药卫生—肿瘤] R96 [医药卫生—药理学]
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参考文献15

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二级参考文献20

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共引文献16

同被引文献10

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引证文献1

二级引证文献6

中华放射肿瘤学杂志
2007年 第6期

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