摘要
目的探讨FK506的肝毒性。方法报告2例肾移植术后应用FK506后,出现转氨酶、胆红素升高。结果1例仅停药后肝功恢复;另1例经停药,保肝治疗后恢复。结论FK506可引起肝脏损害,致转氨酶、胆红素升高,临床应用中注意该项副作用。
Objective To discuss the drug - induced liver damage by FKS06. Methods Clinical data of 2 cases whose alanine aminotransferase（ALT）, bilirubin （T- Bil ） elevating with oral take FKS06 after renal transplantation had been analysed. Results One patient＇s hepatic function had returned normal after stopping FK.506; the other had returned normal after stopping FKS06 and giving liver - protective remedies. Conclusion FKS06 may cause liver damage and liver function, so they should be monitored in renal recipients particularly.
出处
《临床医学》
CAS
2007年第11期5-7,共3页
Clinical Medicine
关键词
FK506
肝毒性
药物副作用
Tacrolimus
Hepatotocxicity
Adverse drug reactions
