1404例冠心病合并与不合并2型糖尿病患者冠状动脉造影特点对照分析

Contrasting the characteristic of coronary artery angiography between coronary arterial disease patients with diabetes and without diabetes

目的对照分析冠心病合并与不合并2型糖尿病患者冠状动脉造影的特点。方法对照分析2004年4月至2004年12月于阜外心血管病医院行冠状动脉造影的702例冠心病合并糖尿病患者(DM组)和702例冠心病不合并糖尿病患者(NDM组)的临床资料。冠心病定义为至少有一支主要冠状动脉或其主要分支狭窄≥50%,糖尿病诊断标准参照1999年WHO糖尿病诊断标准,用冠状动脉病变总记分(CLS)评价病变。结果①DM组高血压和高血脂的比例显著高于NDM组,DM组EF值显著低于NDM组(P均<0.05)。②DM组冠状动脉病变总记分明显高于NDM组,多支病变及弥漫性病变比例显著高于NDM组,单支病变比例显著低于NDM组(P均<0.05)。结论2型糖尿病加重冠状动脉病变程度,冠状动脉病变以多支、弥漫性病变多见。

Objective To analyze the characteristic of coronary artery angiography between diabetic patients and nondiabetic patients with coronary arterial disease. Methods Among 1404 coronary arterial disease patients,702 patients had diabetes （ DM group） 302 patients had no diabetes （NDM group）. The definition of diabetes was assessed based on the WHO diagnostic criteria of diabetes mellitus 1999 ,and coronary arterial disease was assessed that more than one main coronary arterial or their main branches were stenosis 〉150%. CLS score were applied to analyzed the coronary artery lesion. Results DM group had significantly higher CIS score than NDM group, and the prevalence of multiple branches and diffusion lesions in diabetic group was 44. 59% ＆ 32. 19% ,significantly higher than that of non -diabetic group （35.33% ＆ 25.37%, P 〈0.05）. Conclusion The extent and severity of angiographie coronary arterial disease is worse in patients with type -2 diabetes than non -diabetic patients. Both the prevalence of multiple branches involvement and diffusion lesions of coronary in the diabetics are higher than that in those without diabetes.