中药R防治食管癌前病变的形态测量学评估

Evaluation of the Effect of Prevention by TCDR on Precursor Lesions of the Esophagus

应用形态测量的方法，对中药R用于食管癌前病变干预治疗结果进行了评价。并与组织学结果进行了比较。结果显示：基底细胞层厚度在治疗前后统计学显示差异有显著性（P＜0．001）。而乳头高度，乳头相对高度和上皮厚度在治疗前后则无统计学意义。组织学结果经配对t检验显示两组间在治疗前后无统计学意义。结果显示：形态测量学可更客观反映组织的病理改变。中药R对改善食管癌前病变中的基底细胞增生可能有一定效果。

on the treatment of precursor lesions of the be and was Compared with histologic features. It was found tha basal cell zone was greatly improved after treatment (P < 0.001). However,the heigh and the relative height of bona Propia papillae and epithelial thickness were not statistically significant before and after treatment The matehed - pair test indicatal tha no statistic ffere was bon the R group and the placebe group by histologic examination . It is suggested that the morphometric measurement is on objective than histologic findings Thiss study showed tha traditional Chinese herb R can reduce the basal cell hyperplasia.