甲状腺癌术后生存率估计及预后因素分析

The Survival Rate and Prognostic Factors in Thyroid Carcinoma

本研究选用了1984年2月至1990年12月期间在河南省肿瘤医院接受手术治疗的甲状腺癌224例，对其术后生存率进行估计，同时对一些影响预后的诸因素作了预后因素分析。单因素分析结果显示：性别、年龄、血管浸润、软组织浸润及病理类型各组间的生存分布有统计学意义（P＜0.05）。应用COX风险比模型进行多因素分析得出有显著意义的预后因素为：年龄、包膜浸润及病理类型。年龄大于对岁，有包膜浸润及病理类型为滤泡状腺癌、髓样癌和其它类型者对预后不利。这些因素的风险比分别为5．91、10．78、15．69、6．92和167．

In thes Study are select 224 cases of thpoid careinorna after operation in Henan bo Hospida in l984~1990. The swhval rate of thyroid ereinoma ther operation was estimated and some prognostic factors were analyed,In single factor analsis the variables which showed statishcall siedcan(P <0. 05) t0 survival distribution were sex, age, invahon of bha vessels and of soft hssues; and Pathobocal types. Using COX proponional hazard moodel to do multiple factor analsis, the variables tha were connsidetal in analysis as potentially influencing swhval factors were age, invasion of capeul and Pathobocal types. Statistically siedficant(P < 0.O5) ptalictors of wome survival were old age (over than 50years ), invasion of capsule, foilicular type, medullary type and other undifferentiated types. The hazard ratios were 5 .9l, l0.78, 15 .69,9.62 and l67 .06 respectively.