摘要
对127例SLE患者作了1∶1病例对照研究。结果,单因素分析P≤0.1的因素有经常生冻疮、潮湿环境、结核病史、曾用异烟肼、药物过敏、中耳炎病史、带状疱疹、有害物接触、多食油脂食物和红斑狼疮家族史。多因素条件Logistic回归分析显示与SLE有关的可能危险因素有:红斑狼疮家族史(OR=19.47)、多食油脂食物(2.41)、有害物接触史(2.84)等,PAR%分别为9.5%、17.0%和10.6%。带状疱疹、结核病史可能为诱发因素或早期伴随的疾病。多食油脂食物与有害物接触有协同作用。
A 1∶1 matched case control study on systemic lupus erythematosus (SLE) patients from Shanghai was conducted.Univariate analysis showed that factors related to SLE(P≤0.1) were frequent chilblain,humid environment,history of tuberculosis,isoniazid administration,drug allergy,history of otitis media,history of herpes zoster,exposure of harmful chemicals,
关键词
系统性红斑狼疮
对照研究
危险因素
Systemic lupus erythematosus\ Case control study\ Risk factors