2200名不孕症患者病因分析

Investigation of the Pathogenesis for the Infertility

【目的】探讨不孕症病因的变化以指导相应的预防和治疗。【方法】分析2 200名不孕症类型及病因的变化。【结果】①继发不孕症比率明显提高;②输卵管性因素、子宫内膜异位症、多囊卵巢综合征及男性因素的比例分别为40.1%、30.05%、33%和32.77%;③继发不孕症患者性伴侣明显多于原发不孕(P<0.05);④宫颈炎发病率为34.4%,11.2%患者有过异位妊娠病史,盆腔结核占6.2%,宫颈分泌物解脲支原体(UU)感染率64.25%,沙眼衣原体(CT)感染率为7.86%。【结论】输卵管性因素、子宫内膜异位症、多囊卵巢综合征及男性因素是不孕症的主要原因,继发不孕症增多与婚前越来越开放的性行为有关。

[Objective]To explore the pathogenesis of infertility for directing the methods of treatment and prevention. [Methods]Twenty-two-hundred cases of infertility were selected in order to discover the types and pathogenesis of the infertility. [Results]（1）The rate of secondary infertility was visibly increased. （2）The rates of oviducal factors, endometriosis,polycystic ovarian syndrome （PCOS） and the male cause were 40. 1%,30. 05% ,33% and 32.77% respectively;（3）The partner number of secondary infertility was significantly more than the primary （ P〈0.05）;（4）The rates of cervicitis, ectopic pregnancy, pelvic TB were respectively 34. 4% 11.2%,6.2%. The infection rates of CT and UU in cervical secretion were 7.86% and 64.25%. [Conclusion] The factors of fallopian tube,endometriosis,PCOS and the male cause are the most important pathogenesis of the infertility. The rate of secondary infertility is incerased, and this situation is due to open sexual behavior before marriage.