不同浓度的罗哌卡因分娩镇痛效果观察

Effect observation of different concentration ropivacaine with fentany on delivery analgesia

目的比较三种不同浓度罗哌卡因伍用芬太尼用以硬膜外分娩镇痛的效果。方法90例要求分娩镇痛的孕妇随机分成0.15%罗哌卡因组(Ⅰ组)、0.125%罗哌卡因组(Ⅱ组)、0.1%罗哌卡因组(Ⅲ组),均复合芬太尼(2μg/ml),硬膜外自控镇痛(PECA)速率6ml/h,自控3ml/次,锁定时间15min。以VAS评评分比较三组分娩镇痛后PCEA的效果。Bromage评分评定运动阻滞情况。结果镇痛后10、30、60、120、180、240minVAS评分Ⅲ组显著高于Ⅰ、Ⅱ组;Bromage评分Ⅰ组显著高于Ⅱ、Ⅲ组,Apgar评分差异无统计学意义。无明显不良反应。结论0.125%罗哌卡因复合芬太尼对孕妇行分娩镇痛效果确切,无明显不良反应,适合临床应用。

Objective To compare the effect of epidural analgesia application of three concentration combined with fentany on dlivery.Methods Ninty puerpera asking for delivery analgesia were divided into three groups,0.15% ropivacaine（group Ⅰ）,0.125%（group Ⅱ）,0.1%（group Ⅲ）,combined fentany （2 μg/ml）,PECA 6 ml/h,PCA 3 ml/p,lockout time 15 min.The PCEA on delivery analgesia was measured in 15 min.The PCEA on delivery analgesia was measured by Vas scores.The never block was observed by Bromage scores.Results VAS score of analgesia in 10,30,60,120,180,240 min,group Ⅲ was better than group Ⅰ and Ⅱ.Bromge scores were higher than group Ⅱ,Ⅲ.Apgar scores were no significantly different.Conclusion 0.125% ropivacaine combined with fentany has good effect on delivery analgesia.It is practicable clinicany.