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非酒精性脂肪肝与胰岛素抵抗及血脂异常的研究 被引量:4

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摘要 目的:探讨非酒精性脂肪肝(NAFLD)与胰岛素抵抗及血脂异常的关系。方法:随机选取长江水利委员会2006年职工健康体检NAFLD患者100例,排除饮酒、病毒性肝炎、自身免疫性肝炎、药物性肝损害及糖尿病者。同时随机选择32例年龄、性别相匹配的正常对照者,检测空腹血糖、血脂等指标。结果:NAFLD组与正常对照组相比,空腹血糖(FPG)、甘油三脂(TG)明显升高(P<0.05),HDL明显降低(P<0.05)。结论:非酒精性脂肪肝患者存在着明显的胰岛素抵抗及脂质代谢异常,与正常对照组比较有显著性差异,提示胰岛素抵抗及脂质代谢异常在脂肪肝发病中具有十分重要的地位,胰岛素抵抗可能是脂肪肝原发病理基础。
出处 《数理医药学杂志》 2007年第6期887-888,共2页 Journal of Mathematical Medicine
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