成人麻疹住院病例63例分析

Clinical analysis on 63 adult measles patients.

目的分析成人麻疹患者的临床、实验室及流行病学特点,为控制成人麻疹流行提供依据。方法回顾性分析63例成人麻疹住院患者。结果患者的平均年龄为26.67±7.09岁,前驱期4.19±2.19d。63例患者均有发热,且以39.1—40.0℃为多。63例患者均有皮疹,71.4%的患者入院时可见到麻疹黏膜斑。31.7%的患者并发支气管炎及支气管周围炎。ALT及AST升高者分别占41.1%和46.4%,LDH-L升高者占75.0%,HBDH升高者48.2%,CK升高者28.6%。结论近年来,成人麻疹发病率有上升的趋势,且患者临床表现较重,并发症较常见。是否应对高危人群的成年人进行强化免疫,值得相关部门探讨和关注。

Objective To find out the clinical, laboratory and epidemic features of adult measles and provide theoretic evidence for measles control. Methods Data of 63 hospitalized adult measles cases was analyzed retrospectively. Results Average age was 26.67 ± 7.09 years old and the prodromal period was 4.19±2.19 days. All patients had a temperature, most of them had high fever between 39. 1℃ to 40.0℃. All patients had rashes and Koplic＇ s spots was noted in 71.4% patients. Bronchitis and peribronchitis were found in 31.7 % patients, raised ALT and AST were found in 41.1% and 46.4% patients respectively, 75.0% patients was detected with raised LDH - L, 48.2% cases with raised HBDH and 28.6% cases with raised CK level were also detected. Conclusions Incidence of adult measles has a adscendent tendency in recent years. Measles patients in adult usually have sever clinical manifestation and complications are common. Application of Mva immunization to adults in high risk is a subject that is worth to concern and discuss.