乙肝病毒感染与大肠癌肝转移关系

Relationship between hepatic metastasis and hepatitis B virus infection in colorectal cancer

目的探讨乙肝病毒感染与大肠癌肝转移的关系。方法回顾性分析1996年1月～2005年12月收治的大肠癌患者386例,比较乙肝病毒感染的大肠癌和非乙肝病毒感染的大肠癌两组肝转移的发生率。结果乙肝病毒感染组肝转移发生率为8.6%,非乙肝病毒感染组肝转移发生率为23.5%,两者相比差异显著(P<0.05)。结论乙肝病毒感染的大肠癌肝转移发生率比非乙肝病毒感染组低,前者很少发生肝转移。

Objective To explore the relationship between HBV infection and hepatic melastasis of colorectal cancer. Methods Three hundred and eighty - six cases with colorectal cancer were retrospectively analyzed from January 1996 to Decemer 2005,and the prevalence of hepatic metastasis of colorectal cancer in patients with and without hepatitis B vires infection was compared. Results In the HBV carriers, the prevalences of hepatic metastasis were 8.6% and that in non - HBV carriers was 23.5 %, showing significant difference between the two groups （ P 〈 0.05 ）. Conclusion The prevalence of homochronous hepatic metastasis and heterochronous hepatic metastasis of colorectal cancer in patients with HBV infection is lower than that of non - HBV infection group. Hepatic metastasis of colorectal cancer is infrequent in pateints with HPV infection.