铜络合物催化β-(-)-蒎烯的不对称环丙烷化反应

Asymmetric Cyclopropanation of β-(-)-Pinene Catalyzed by Copper Complexes

分别用水杨醛铜、β-二酮-铜和希夫碱-铜络合物为催化剂进行β-(-)-蒎烯与重氮乙酸酯的不对称环丙烷化反应,研究了催化剂结构与反应立体选择性之间的关系,获得了较高的立体选择性.

The asymmetric cyclopropanation of β-（ - ）-pinene with diazoacetate was performed in the presence of copper salicylaldehydate, copper diketonates, and copper-Schiff base complexes as the catalyst, respectively. The relationship between the stereoselectivity for the reaction and structure of the copper-Schiff base was studled, and high stereoselectivity was achieved.