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新型超低温探头在分析与科研中的应用 被引量:2

A Review on Technical Innovations and Applications of Bruker CryoProbes^(TM)
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摘要 过去的几十年里,超低温探头技术是使得NMR灵敏度得到极大提高的技术上的唯一进步.本文详细介绍了布鲁克各种类型超低温探头的技术创新和应用实验.布鲁克超低温探头在灵敏度上的飞跃,使得科学家可以研究以前无法研究的小量样品,样品测试的通量最高可增加16倍.各种新型的超低温探头也将把超低温探头的应用扩展到新的领域. Bruker's CryoProbes^TM show large improvement in terms of NMR detection sensitivity over the last few decades. This paper provides a detailed review on the technical innovation and applications of various Bruker CryoProbes^TM. The large increase of detection sensitivity of CryoProbesTM enables experiments on samples with amounts that were considered too small just a few years ago to have reliable results. With the Cryo- Probes^TM, sample throughput can also be increased up to 16-fold. With the increasing variety of CryoProbe models, the applications of Cryoprobes^TM will expand further into other new fields.
出处 《波谱学杂志》 CAS CSCD 北大核心 2007年第4期526-534,共9页 Chinese Journal of Magnetic Resonance
关键词 核磁共振 超低温探头 综述 天然产物 生物大分子 NMR, CryoProbe^TM, overview, natural product, biological macromolecule
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参考文献4

  • 1Kovacs H, Moskau D, Spraul M. Cryogenically cooled probes-a leap in NMR technology progress in nuclear magnetic resonance spectroscopy[J]. Prog NMR Spectrosc, 2005, 46: 131-155.
  • 2Heus H A, Wijmenga S S, Van de Ven F J M, et al. Sequential backbone assignment in ^13C-Labeled RNA via through-bond coherence transfer using three-dimensional triple resonance spectroscopy (^1H ,^13C, ^31p) and two- dimensional hereto TOCSY[J]. J Am Chem Soc, 1994, 116:4 983-4 984.
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