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HSP27表达与肿瘤耐药关系的研究进展 被引量:2

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摘要 热休克蛋白27(heat shock protein 27,HSP27),又名热休克蛋白B1(heat shock protein B1,HSPB1)、热休克蛋白25(heat shock protein 25,HSP25),是热休克蛋白家族中的小分子热休克蛋白亚家族(sHSP亚家族)的重要一员。近年HSP27与肿瘤的关系引人注目,而肿瘤耐药是影响肿瘤临床预后的重要方面,本文就HSP27和肿瘤耐药的关系作一综述。
出处 《浙江医学》 CAS 2007年第11期1238-1241,共4页 Zhejiang Medical Journal
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参考文献22

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同被引文献19

  • 1CIOCCA D R,CALDERWOOD S K. Heat shock proteins in canc-er :diagnostic,prognostic,predictive,and treatment implications[J]. Cell Stress Chaperones, 2005,10(2) : 86 - 103.
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  • 3LANNEAU D, BRUNET M,FRISAN E, et al. Heat shock pro-teins :essential proteins for apoptosis regulation [ J ]. J Cell MolMed, 2008, 12(3) : 743 -761.
  • 4DIDELOT C, SCHMITT E, BRUNET M, et al. Heat shock pro-teins :endogenous modulators of apoptotic cell death [ J ]. HandbExp Pharmacol, 2006(172) : 171 -198.
  • 5CONCANNON C G, GORMAN A M, SAMALI A. On the role of Hsp27 in regulating apoptosis[J]. Apoptosis, 2003, 8( 1 ) : 61 -70.
  • 6CTCALLAGHAN SUNOL C, GABAI V L, SHERMAN M Y.Hsp27 modulates p53 signaling and suppresses cellular senescence[J]. Cancer Res, 2007, 67(24) : 11779 -11788.
  • 7KEEZER S M,IVIE S E,KRUTZSCH H C, et al. Angiogenesisinhibitors target the endothelial cell cytoskeleton through alteredregulation of heat shock protein 27 and cofilin [ J]. Cancer Res,2003, 63(19) : 6405 -6412.
  • 8SONG T F,ZHANG Z F, LIU L,et al. Small interfering RNA -mediated silencing of heat shock protein 27 ( HSP27 ) increaseschemosensitivity to paclitaxel by increasing production of reactiveoxygen species in human ovarian cancer cells ( H08910) [ J ]. JInt Med Res, 2009, 37(5) : 1375 -1378.
  • 9高红军(综述),赵晓航(审校).热休克蛋白105在肿瘤应用基础领域的研究进展[J].肿瘤研究与临床,2009,21(10):713-715. 被引量:1
  • 10何美安,周莉,程龙献,张晓敏,郭欢,王芳,邬堂春.白介素-1A(IL-1A)和IL-1B基因多态性与冠心病关系的病例-对照研究[J].环境与职业医学,2010,27(8):476-479. 被引量:3

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