Avastin(贝伐单抗)联合化疗治疗晚期恶性肿瘤临床观察

Clinical Observation of Advanced Tumor Patients Treated by Avastin Combined with Chemotherapy

目的观察Avastin(贝伐单抗)联合化疗治疗晚期恶性肿瘤的疗效和安全性。方法Avastin的用法为5 mg/kg,在化疗的第2天静滴,2周后重复,至少用4次。化疗方案不限,采用3周重复,一般完成3个周期化疗与使用4次Avastin治疗同步,即评定疗效。结果9例中PR 2例,SD 6例,PD 1例。毒副反应轻微可以耐受。结论该治疗方法显示了Avastin作为肿瘤分子靶向联合化疗的广阔前景。

Objective To observe the effect and security of advanced tumor patients treaded by Avastin combined with chemotherapy. Methods. The usage of Avastin is 5 mg/kg, in the chemotherapy second day , after two weeks repeated, at least uses 4 times. The chemotherapy plan does not limit, uses 3 week repeated, generally completed 3 cyclical chemotherapies with use 4 times of Avastin just synchronization, namely evaluates the curative effect. Results The cases of PR, SD and PD in 9 patients were 2, 6 and 1 with mild toxicity. Conclusions Avastin as a target drug will show vast foreground of treatment.