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血管紧张素转换酶2在心血管系统中的意义 被引量:3

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摘要 血管紧张素转换酶2(ACE2)是2000年才发现的肾素-血管紧张素系统的新成员,主要表达于心脏、肾脏和睾丸。ACE2的主要生物学效应是降解血管紧张素II(AngII)产生Ang1-7,Ang1-7具有舒张血管、抗增生、抗炎症的作用,对衰竭心脏有保护作用。研究发现ACE2基因敲除小鼠心功能受损,AngII水平升高。本文综述了ACE2的生物学效应以及在心血管系统中的意义。
出处 《心脏杂志》 CAS 2007年第6期723-725,共3页 Chinese Heart Journal
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参考文献15

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二级参考文献6

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