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特发性血小板减少性紫癜中的T、B细胞异常

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摘要 特发性血小板减少性紫癜(ITP)是一组无明显外源性病因引起血小板减少的异质性疾病,不同患者所涉及、所主导的发病环节可能不同,其中T、B细胞所起的作用尤为重要。深入开展ITP患者T、B细胞异常的研究将有助于对ITP发病机制的认识和疾病分层后的个体化治疗。本文介绍了ITP患者自身反应性T细胞的异常产生,T、B细胞的异常激活和T细胞亚群失衡,所导致的血小板破坏效应阶段。
出处 《国际输血及血液学杂志》 CAS 2007年第6期509-512,共4页 International Journal of Blood Transfusion and Hematology
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